Endocrine Abstracts

Background: Cardiovascular stratification and prevention in type 2 diabetic patients represent a major public health preoccupation in order to reduce their mortality. Several methods of detecting atherosclerosis have been developed such as biomarkers. The aim of this study was to evaluate the association between B-type natriuretic peptide (BNP) and cardiovascular risk (CVR) in type 2 diabetic patients.Methods: We conducted a cross-sectional study in 71 t...

Introduction: Sheehan’s syndrome (SS) is defined as partial or complete hypopituitarism occurring due to massive postpartum uterine hemorrhage that leads to pituitary infarction. Patients with SS have varying degrees of anterior pituitary hormone deficiency. The aim of our study was to evaluate the clinical and hormonal characteristics of patients with SS.Methods: Eighteen patients with SS were enrolled in a retrospective and descriptive study. Medi...

Introduction: Sheehan’s syndrome (SS) is postpartum hypopituitarism caused by necrosis of the pituitary gland. Patients with SS have varying degrees of anteriorpituitary hormone deficiency and have an increased mortality from cardiovascular disease. Inadequate hormone replacement is one of the possible causes of this increased mortality. The aim of our study was to assess metabolic and cardiovascular outcome in patients with SS.Methods: In a retrosp...

Introduction: Pituitary metastases are rare complications of malignancy, representing only 1% of surgical tumours of the pituitary gland. They are usually encountered in elderly patients with disseminated malignant disease. The most frequent are metastases of breast and lung cancer. In this report, we describe a rare case of a metastatic breast cancer to the pituitary gland.Observation: A 32-year-old female presented with blurred vision and diminished vi...

Introduction: Papillary thyroid carcinomas (PTC) represent up to 87% of all thyroid cancers with an incidence that has doubled over the past 30 years. Hashimoto’s thyroiditis (HT) and Graves’ disease are two autoimmune thyroid diseases representing the most common causes of hypothyroidism and hyperthyroidism, respectively. Although PTC with coexisting HT has been reported in literature, its association with GD is not a common condition. Herein, we report three cases ...

Introduction: Retrospective analysis has shown that approximately 17–84% of patients suffering from primary hyperparathyroidism have a concomitant thyroid disease. However, it still remains controversial whether these two pathologies happen coincidental or are caused by specific risk factors or genetic changes. In this study we aimed to evaluate concurrently detected thyroid pathologies in patients who underwent surgery for primary hyperparathyroidism.<p class="abstex...

Introduction: Polycystic ovary syndrome (PCOS) is a heterogeneous disorder, characterized by chronic anovulation and hyperandrogenism. Hirsutism, defined as excessive terminal hair that appears in a male pattern in a woman, is frequently present in patients with PCOS. We aimed to determine the clinical and biological characteristics of hirsute patients with PCOS.Methods: It was a retrospective study included 30 women diagnosed with PCOS according to the ...

Introduction: The reactive pituitary gland enlargement is a non-neoplastic growth of at least one pituitary lineage, which can often be essential or secondary to prolonged deficit of a gland target. It may be difficult to differentiate from functional pituitary adenomas. Herein we report a case of pituitary hyperplasia secondary to congenital primary hypothyroidism diagnosed at the age of 38 years.Observation: A 38-year-old female patient presented with ...

Introduction: Myasthenia gravis is an autoimmune neuromuscular disease characterized by the presence of anti-acetylcholine receptor antibodies. It can be isolated or associated with other auto-immune conditions. Graves’ disease is an autoimmune disorder typically characterized by the presence of circulating autoantibodies that tie to and stimulate the thyroid hormone receptor. Coexisting myasthenia gravis and Graves’ disease is a rare but well recognized condition. T...

IntroductionPhaeochromocytomas are rare neuroendocrine tumors secreting high levels of catecholamines, able to exert serious metabolic and cardiovascular effects. Glucose intolerance are common complications that require an early recognition and treatment.MethodsA retrospective study was conducted to assess the prevalence of metabolic and cardiovascular complications in 35 patients diagnosed with pheochromocy...